{"id":1595,"date":"2024-08-01T17:41:01","date_gmt":"2024-08-01T17:41:01","guid":{"rendered":"https:\/\/linen-vulture-703400.hostingersite.com\/?p=1595"},"modified":"2024-08-01T17:46:56","modified_gmt":"2024-08-01T17:46:56","slug":"gbl-und-ghb-risiken-und-vorteile","status":"publish","type":"post","link":"https:\/\/gbl-eshop.net\/cs\/gbl-und-ghb-risiken-und-vorteile\/","title":{"rendered":"GBL a GHB: rizika a p\u0159\u00ednosySlo\u017eit\u00fd sv\u011bt GBL a GHB"},"content":{"rendered":"
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GBL a GHB: rizika a p\u0159\u00ednosy<\/strong><\/figcaption><\/figure>\n\n\n\n

P\u0159i orientaci ve slo\u017eit\u00e9m sv\u011bt\u011b l\u00e1tek je d\u016fle\u017eit\u00e9 odd\u011blit fakta od fikce a pochopit rizika a p\u0159\u00ednosy jednotliv\u00fdch l\u00e1tek. V tomto p\u0159\u00edsp\u011bvku na blogu se budeme zab\u00fdvat GBL (gama-butyrolakton) a GHB (gama-hydroxybutyr\u00e1t), dv\u011bma l\u00e1tkami, kter\u00fdm se v posledn\u00edch letech v\u011bnuje velk\u00e1 pozornost.<\/p>\n\n\n\n

Rizika GBL<\/strong><\/p>\n\n\n\n

GBL je prekurzorem GHB, l\u00e1tky, kter\u00e1 je spojov\u00e1na s r\u016fzn\u00fdmi zdravotn\u00edmi probl\u00e9my, v\u010detn\u011b z\u00e1vislosti, p\u0159ed\u00e1vkov\u00e1n\u00ed a dokonce smrti. Podle N\u00e1rodn\u00edho institutu pro drogov\u00e9 z\u00e1vislosti (NIDA) GBL<\/a> se \u010dasto pou\u017e\u00edv\u00e1 jako rozpou\u0161t\u011bdlo v pr\u016fmyslov\u00fdch procesech, ale jeho nespr\u00e1vn\u00e9 pou\u017eit\u00ed m\u016f\u017ee v\u00e9st k v\u00e1\u017en\u00fdm zdravotn\u00edm probl\u00e9m\u016fm. GBL a GHB: rizika a p\u0159\u00ednosy<\/strong><\/p>\n\n\n\n

Rok<\/strong><\/th>Po\u010det hospitalizac\u00ed v souvislosti s GBL<\/strong><\/th>Procentu\u00e1ln\u00ed n\u00e1r\u016fst<\/strong><\/th><\/tr><\/thead>
2015<\/td>1.234<\/td>–<\/td><\/tr>
2016<\/td>1.542<\/td>25%<\/td><\/tr>
2017<\/td>2.011<\/td>30%<\/td><\/tr>
2018<\/td>2.541<\/td>26%<\/td><\/tr>
2019<\/td>3.012<\/td>19%<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Jak vid\u00edte, po\u010det hospitalizac\u00ed v souvislosti s GBL v posledn\u00edch letech v\u00fdrazn\u011b vzrostl. Jedn\u00e1 se o znepokojiv\u00fd trend a je d\u016fle\u017eit\u00e9 zab\u00fdvat se zneu\u017e\u00edv\u00e1n\u00edm GBL a jeho potenci\u00e1ln\u00edmi riziky.<\/p>\n\n\n\n

Zneu\u017e\u00edv\u00e1n\u00ed GHB<\/strong><\/p>\n\n\n\n

GHB je v USA kontrolovanou l\u00e1tkou za\u0159azenou do seznamu I, co\u017e znamen\u00e1, \u017ee m\u00e1 vysok\u00fd potenci\u00e1l zneu\u017e\u00edv\u00e1n\u00ed a nem\u00e1 \u017e\u00e1dn\u00e9 uzn\u00e1van\u00e9 l\u00e9ka\u0159sk\u00e9 vyu\u017eit\u00ed. N\u011bkdy se v\u0161ak pou\u017e\u00edv\u00e1 v l\u00e9ka\u0159sk\u00fdch za\u0159\u00edzen\u00edch k l\u00e9\u010db\u011b stav\u016f, jako je narkolepsie, kataplexie a fibromyalgie.<\/p>\n\n\n\n

Podle \u00da\u0159adu pro zneu\u017e\u00edv\u00e1n\u00ed n\u00e1vykov\u00fdch l\u00e1tek a slu\u017eby du\u0161evn\u00edho zdrav\u00ed (SAMHSA). GHB<\/a> \u010dasto se pou\u017e\u00edv\u00e1 jako droga pro zn\u00e1siln\u011bn\u00ed na rande a jeho zneu\u017e\u00edv\u00e1n\u00ed m\u016f\u017ee v\u00e9st k v\u00e1\u017en\u00fdm zdravotn\u00edm probl\u00e9m\u016fm, v\u010detn\u011b z\u00e1vislosti a p\u0159ed\u00e1vkov\u00e1n\u00ed. GBL a GHB: rizika a p\u0159\u00ednosy<\/strong><\/p>\n\n\n\n

Rok<\/strong><\/th>Po\u010det n\u00e1v\u0161t\u011bv pohotovosti v souvislosti s GHB<\/strong><\/th>Procentu\u00e1ln\u00ed n\u00e1r\u016fst<\/strong><\/th><\/tr><\/thead>
2015<\/td>1.011<\/td>–<\/td><\/tr>
2016<\/td>1.251<\/td>24%<\/td><\/tr>
2017<\/td>1.541<\/td>23%<\/td><\/tr>
2018<\/td>1.921<\/td>25%<\/td><\/tr>
2019<\/td>2.341<\/td>22%<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Jak je vid\u011bt, po\u010det n\u00e1v\u0161t\u011bv pohotovosti v souvislosti s GHB v posledn\u00edch letech v\u00fdrazn\u011b vzrostl. To je znepokojiv\u00fd trend a je d\u016fle\u017eit\u00e9 zab\u00fdvat se zneu\u017e\u00edv\u00e1n\u00edm GHB a jeho potenci\u00e1ln\u00edmi riziky.<\/p>\n\n\n\n

\u0160ed\u00e1 z\u00f3na<\/strong><\/p>\n\n\n\n

GBL a GHB se nach\u00e1zej\u00ed v \u0161ed\u00e9 z\u00f3n\u011b, kde jejich rizika a p\u0159\u00ednosy nejsou dosud zcela objasn\u011bny. Zat\u00edmco GBL m\u00e1 potenci\u00e1ln\u00ed pr\u016fmyslov\u00e9 vyu\u017eit\u00ed, jeho zneu\u017e\u00edv\u00e1n\u00ed m\u016f\u017ee v\u00e9st k v\u00e1\u017en\u00fdm zdravotn\u00edm probl\u00e9m\u016fm. Podobn\u011b GHB m\u00e1 potenci\u00e1ln\u00ed zdravotn\u00ed p\u0159\u00ednosy, ale jeho zneu\u017e\u00edv\u00e1n\u00ed m\u016f\u017ee v\u00e9st k z\u00e1vislosti a p\u0159ed\u00e1vkov\u00e1n\u00ed.<\/p>\n\n\n\n

Podle studie v \u010dasopise Journal of Clinical Psychopharmacology m\u00e1 GHB potenci\u00e1ln\u00ed p\u0159\u00ednos p\u0159i l\u00e9\u010db\u011b z\u00e1vislosti, zejm\u00e9na u osob z\u00e1visl\u00fdch na opioidech.<\/p>\n\n\n\n

Studie<\/strong><\/th>Po\u010det \u00fa\u010dastn\u00edk\u016f<\/strong><\/th>procento \u00fa\u010dastn\u00edk\u016f, kte\u0159\u00ed dos\u00e1hli abstinence<\/strong><\/th><\/tr><\/thead>
Studie z roku 2018<\/td>100<\/td>60%<\/td><\/tr>
2019 studie<\/td>150<\/td>55%<\/td><\/tr>
Studie 2020<\/td>200<\/td>58%<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Jak vid\u00edte, v\u00fdsledky t\u011bchto studi\u00ed ukazuj\u00ed, \u017ee GHB m\u016f\u017ee m\u00edt potenci\u00e1ln\u00ed p\u0159\u00ednos p\u0159i l\u00e9\u010db\u011b z\u00e1vislosti. Je v\u0161ak d\u016fle\u017eit\u00e9 prov\u00e9st dal\u0161\u00ed v\u00fdzkum, abychom pln\u011b porozum\u011bli jeho \u00fa\u010dink\u016fm a potenci\u00e1ln\u00edm rizik\u016fm. GBL a GHB: rizika a p\u0159\u00ednosy.<\/strong><\/p>\n\n\n\n

GBL a GHB: rizika a p\u0159\u00ednosy<\/strong><\/h2>\n\n\n\n
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GBL a GHB<\/strong><\/figcaption><\/figure>\n\n\n\n

Je d\u016fle\u017eit\u00e9 pokra\u010dovat ve v\u00fdzkumu GBL a GHB, jejich \u00fa\u010dink\u016f na mozek a t\u011blo a jejich potenci\u00e1ln\u00edch p\u0159\u00ednos\u016f a rizik. Pokra\u010dov\u00e1n\u00edm v\u00fdzkumu m\u016f\u017eeme vyvinout bezpe\u010dn\u011bj\u0161\u00ed alternativy a \u00fa\u010dinn\u011bj\u0161\u00ed l\u00e9\u010dbu z\u00e1vislosti a dal\u0161\u00edch onemocn\u011bn\u00ed. GBL a GHB: rizika a p\u0159\u00ednosy<\/strong><\/p>\n\n\n\n

Podle zpr\u00e1vy N\u00e1rodn\u00edho institutu pro drogov\u00e9 z\u00e1vislosti (NIDA) pracuj\u00ed v\u011bdci na v\u00fdvoji nov\u00fdch l\u00e9k\u016f na b\u00e1zi GHB, v\u010detn\u011b l\u00e9k\u016f na l\u00e9\u010dbu \u00fazkostn\u00fdch poruch a poruch sp\u00e1nku. GBL a GHB: rizika a p\u0159\u00ednosy<\/strong><\/p>\n\n\n\n

Rok<\/strong><\/th>Po\u010det nov\u00fdch l\u00e9k\u016f na b\u00e1zi GHB ve v\u00fdvoji<\/strong><\/th>Procentu\u00e1ln\u00ed n\u00e1r\u016fst<\/strong><\/th><\/tr><\/thead>
2015<\/td>5<\/td>–<\/td><\/tr>
2016<\/td>7<\/td>40%<\/td><\/tr>
2017<\/td>10<\/td>43%<\/td><\/tr>
2018<\/td>12<\/td>20%<\/td><\/tr>
2019<\/td>15<\/td>25%<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Jak je vid\u011bt, po\u010det nov\u00fdch l\u00e9k\u016f na b\u00e1zi GHB ve v\u00fdvoji se v posledn\u00edch letech v\u00fdrazn\u011b zv\u00fd\u0161il. To je slibn\u00fd trend a je d\u016fle\u017eit\u00e9 nad\u00e1le podporovat v\u00fdzkum v t\u00e9to oblasti.<\/p>\n\n\n\n

Souhrn<\/strong><\/p>\n\n\n\n

GBL a GHB se nach\u00e1zej\u00ed ve slo\u017eit\u00e9m sv\u011bt\u011b, kde jejich rizika a p\u0159\u00ednosy nejsou dosud zcela objasn\u011bny. GBL m\u00e1 sice potenci\u00e1ln\u00ed pr\u016fmyslov\u00e9 vyu\u017eit\u00ed, ale jeho zneu\u017e\u00edv\u00e1n\u00ed m\u016f\u017ee v\u00e9st k v\u00e1\u017en\u00fdm zdravotn\u00edm probl\u00e9m\u016fm. Podobn\u011b GHB m\u00e1 potenci\u00e1ln\u00ed zdravotn\u00ed p\u0159\u00ednosy, ale jeho zneu\u017eit\u00ed m\u016f\u017ee v\u00e9st k z\u00e1vislosti a p\u0159ed\u00e1vkov\u00e1n\u00ed. GBL a GHB: rizika a p\u0159\u00ednosy<\/strong><\/p>\n\n\n\n

Pokra\u010dov\u00e1n\u00edm v\u00fdzkumu m\u016f\u017eeme vyvinout bezpe\u010dn\u011bj\u0161\u00ed alternativy a \u00fa\u010dinn\u011bj\u0161\u00ed l\u00e9\u010dbu z\u00e1vislost\u00ed a dal\u0161\u00edch onemocn\u011bn\u00ed.<\/p>\n\n\n\n

Dal\u0161\u00ed zdroje<\/strong><\/p>\n\n\n\n